From the east:
Take I-276 Pennsylvania Turnpike heading west.  Take exit 328-King of Prussia/Valley Forge.  After paying the toll, merge onto US-202 South toward West Chester.  Merge right onto US-30 West toward Downingtown/Coatesville. Stay on this bypass. Take the Chester County Airport/Airport Road exit. At the stop sign, turn right onto Airport Road. Highlands Corporate Center will be on the right.

From the north:
Take I-476 Northeast Extension of the Pennsylvania Turnpike heading south.  Take I-276 Pennsylvania Turnpike West.  Take exit 328-King of Prussia/Valley Forge.  After paying the toll, merge onto US-202 South toward West Chester.  Merge right onto US-30 West towards Downingtown/Coatesville.  Stay on this bypass.  Take the Chester County Airport/Airport Road exit.  At the stop sign, turn right onto Airport Road. Highlands Corporate Center will be on the right.

From the south:
Take US-202 North towards Wilmington/West Chester.  Merge left to take PA-100 North.  Take US-30 West toward Downingtown/Coatesville.  Take the Chester County Airport/Airport Road exit.  At the stop sign, turn right onto Airport Road.  Highlands Corporate Center will be on the right.

From the west:
Take the Pennsylvania Turnpike heading east.  Take exit 247-Harrisburg East/Hershey.  After paying the toll, merge onto PA-283 East toward Airport/Lancaster.  PA-283 East becomes US-30 East in Lancaster.  Continue on Business Route US-30 East.  Turn left onto Airport Road.  Highlands Corporate Center will be on the right.